MBOSE first started in 1974, but after 1996, when the University (NEHU) discontinued the Pre-University Course, it was taken over by the Board, since then all the financial matters, relating with SSLC and HSSLC branch were being dealt by the Board itself. Due to the increasing number of students per year, the work load is also increased. After 1996, the Board is handling all the academic matters related with framing of syllabus for all the classes, including SSLC and HSSLC.
The legislation for the setting up of the Meghalaya Board of School Education to regulate, supervise and control school education in the State of Meghalaya came into force on 25th September, 1973 under the Meghalaya Board of School Education Act, 1973 (Meghalaya Act 10, 1973). The Board was inaugurated by the Honourable Chief Minister of Meghalaya, Late Captain W. A. Sangma on 19th October, 1973 in the State Central Library Auditorium, Shillong.Meghalaya Board of School Education has a Cell/Branch at Shillong under an Assistant Secretary entrusted with the MSLC and PSLC Examination works in Khasi and Jaintia Hills. But the Cell now has to take greater responsibilities with the number of Examinations conducted by the Board having increased.